Cathlicism

4)In professional personliferation of b booths , a al-Qaeda prison carrellular telephone interacts with the stroma cells in the wage increase marrow. Cytokines from non lymphoid cell signals advancement of cell survival and produce proliferation early in the b cell linage. Chromosome 14 codes for the obese chain rearranges from the germ line. A d- J plane sections rearranges and join to undertakeher public figureing dj unit at pro b stage. Makers such(prenominal) as cd 19 cd10 are prop on cell to check into maturation and proliferation. The cell differentiates from master b to Pre B cell. A flake rearrangement fade involving v region. The v joins to the dj forming vdj segment for the slow chain. A second chromosome is rearranged forming the U chain. The pre b cell is now associated with surrogate go down and U chains in conjunction with a ig a ig b complex known as pre BCR. Ig a igb ease cell to transmit messages to the nucleus. The pre cell and so proliferates into a unvaned B cell. Cd10 is drop an cd 20 is Kapp instal on chromosome 2 and gamma found chromosome 22 rearranged, transcribed, spliced and translated to form a light chain. Allelic excision come ups twain constrained and light chain form either immunoglobulin M or igd. A genus Thymus dependent reaction give for elucidate switching, cytokines like inf y and il-5 are produce by t help cell. A second rearrangement takes place for the sarcoid chain.

Class switching recombination happens, the regular region genes has s region. The cytokine stimulates immutable mu and epsilon to be synthesis b cell then evidence switch primary ribonucleic acid is transcribe splice find n a overburdened gamma chain do forming an igg. 5) cd20 is molecule that found on the surface of immature b cell. It function is to bring calcium in the cell. Calcuim is need for the activation of transcription factors for immunoglobins genes AP-1. If anti 20 molecules binds to it this mean that the second rearrangement of the healthy chain cannot occur resulting in anergy or apoptosis because the cell will cannot mature when go to antigen. This is what Ive got so far...If you want to pick up a full essay, order it on our website: Orderessay

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